Cerebral radiation necrosis following treatment of extracranial malignancies
نویسندگان
چکیده
منابع مشابه
Conservative treatment of delayed cerebral radiation necrosis.
A 63-year-old man developed delayed cerebral radiation necrosis following radiotherapy to a nasopharyngeal carcinoma. Complete resolution of his neurological deficit resulted from corticosteroid therapy alone. Serial CT scans showed the disappearance of the patients' mass lesion. The literature on cerebral necrosis following radiotherapy of extracranial neoplasms is reviewed with particular emp...
متن کاملIncidence of intracranial radiation necrosis following postoperative radiation therapy for sinonasal malignancies.
OBJECTIVES/HYPOTHESIS Surgery and postoperative radiation therapy are commonly used in the treatment of advanced sinonasal cancer. However, post-treatment radiation changes to the brain often mimic radiologic findings suggestive of tumor recurrence, leading to potential unnecessary intracranial biopsies. The objective of this study was to determine clinical factors that predict signs of tumor r...
متن کاملChallenges with the diagnosis and treatment of cerebral radiation necrosis.
The incidence of radiation necrosis has increased secondary to greater use of combined modality therapy for brain tumors and stereotactic radiosurgery. Given that its characteristics on standard imaging are no different that tumor recurrence, it is difficult to diagnose without use of more sophisticated imaging and nuclear medicine scans, although the accuracy of such scans is controversial. Hi...
متن کاملBevacizumab for the Treatment of Radiation-Induced Cerebral Necrosis: A Systematic Review of the Literature
Radiation necrosis (RN) of brain tissue is a serious late complication of brain irradiation and recently bevacizumab has been suggested as treatment option of RN. There is a lack of data in the literature regarding the effectiveness of bevacizumab for the treatment of RN. The purpose of this review was to perform a comprehensive analysis of all reported cases using bevacizumab for the treatment...
متن کاملReversal of cerebral radiation necrosis with bevacizumab treatment in 17 Chinese patients
BACKGROUND Bevacizumab has been suggested as a new treatment modality for cerebral radiation necrosis due to its ability to block the effects of vascular endothelial growth factor (VEGF) in leakage-prone capillaries, though its use still remains controversial in clinical practice. METHODS The use of bevacizumab in 17 patients with symptomatic cerebral radiation necrosis poorly controlled with...
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ژورنال
عنوان ژورنال: Cancer
سال: 1984
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19841101)54:9<1966::aid-cncr2820540930>3.0.co;2-4